{"id":1760,"date":"2025-02-06T14:46:00","date_gmt":"2025-02-06T17:46:00","guid":{"rendered":"https:\/\/www.ufpb.br\/inova\/?post_type=patente&#038;p=1760"},"modified":"2026-08-18T14:54:07","modified_gmt":"2026-08-18T17:54:07","slug":"peptideos-sinteticos-de-proteinas-estruturais-do-sars-cov-2-para-metodo-de-diagnostico","status":"publish","type":"patente","link":"https:\/\/www.ufpb.br\/inova\/patente\/peptideos-sinteticos-de-proteinas-estruturais-do-sars-cov-2-para-metodo-de-diagnostico\/","title":{"rendered":"Pept\u00eddeos sint\u00e9ticos de prote\u00ednas estruturais do SARS-CoV-2 para m\u00e9todo de diagn\u00f3stico"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A presente inven\u00e7\u00e3o trata de tr\u00eas pept\u00eddeos sint\u00e9ticos selecionados a partir de an\u00e1lises por imunoinform\u00e1tica como ep\u00edtopos imunodominantes derivados da prote\u00edna spike (S) e da prote\u00edna do nucleocaps\u00eddeo (N) do v\u00edrus SARS-CoV-2, e seu uso como ant\u00edgenos em ensaio frente a amostras de pacientes com COVID-19. Diante disso, os pept\u00eddeos foram aplicados em testes de ensaio imunoenzim\u00e1ticos (ELISA indireto) para detectar a presen\u00e7a de anticorpos espec\u00edficos anti-SARS-CoV-2 dos isotipos IgA, IgM e IgG. Os testes permitem diferenciar indiv\u00edduos infectados pelo v\u00edrus SARS-CoV-2 dos n\u00e3o infectados, apresentando 100% de sensibilidade e 100% de especificidade, para todas as dosagens dos anticorpos. Esta inven\u00e7\u00e3o surgiu em necessidade de descoberta de novos marcadores de diagn\u00f3stico imunol\u00f3gico mais espec\u00edficos para a COVID-19.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"451\" src=\"https:\/\/www.ufpb.br\/inova\/wp-content\/uploads\/sites\/79\/sites\/285\/2026\/08\/image-3-1024x451.png\" alt=\"\" class=\"wp-image-1761\" srcset=\"https:\/\/www.ufpb.br\/inova\/wp-content\/uploads\/sites\/79\/sites\/285\/2026\/08\/image-3-1024x451.png 1024w, https:\/\/www.ufpb.br\/inova\/wp-content\/uploads\/sites\/79\/sites\/285\/2026\/08\/image-3-300x132.png 300w, https:\/\/www.ufpb.br\/inova\/wp-content\/uploads\/sites\/79\/sites\/285\/2026\/08\/image-3-768x338.png 768w, https:\/\/www.ufpb.br\/inova\/wp-content\/uploads\/sites\/79\/sites\/285\/2026\/08\/image-3.png 1119w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\" open><summary>Modalidade:<\/summary>\n<p class=\"wp-block-paragraph\">Patente de inven\u00e7\u00e3o<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\" open><summary>Dep\u00f3sito:<\/summary>\n<p class=\"wp-block-paragraph\">06\/02\/2025<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\" open><summary>Carta-patente:<\/summary>\n<p class=\"wp-block-paragraph\"><\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\" open><summary>Transfer\u00eancia tecnol\u00f3gica:<\/summary>\n<p class=\"wp-block-paragraph\">inova@reitoria.ufpb.br<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\" open><summary>Not\u00edcia relacionada:<\/summary>\n<p class=\"wp-block-paragraph\"><\/p>\n<\/details>\n","protected":false},"excerpt":{"rendered":"<p>A presente inven\u00e7\u00e3o trata de tr\u00eas pept\u00eddeos sint\u00e9ticos selecionados a partir de an\u00e1lises por imunoinform\u00e1tica [&hellip;]<\/p>\n","protected":false},"featured_media":1761,"template":"","meta":{"footnotes":""},"patente_type":[22,23],"class_list":["post-1760","patente","type-patente","status-publish","has-post-thumbnail","hentry","patente_type-quimica-materiais","patente_type-saude-bem-estar"],"_links":{"self":[{"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/patente\/1760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/patente"}],"about":[{"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/types\/patente"}],"version-history":[{"count":1,"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/patente\/1760\/revisions"}],"predecessor-version":[{"id":1762,"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/patente\/1760\/revisions\/1762"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/media\/1761"}],"wp:attachment":[{"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/media?parent=1760"}],"wp:term":[{"taxonomy":"patente_type","embeddable":true,"href":"https:\/\/www.ufpb.br\/inova\/wp-json\/wp\/v2\/patente_type?post=1760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}